Mark E Curtis
The geometry of DNA: a structural revision
- critical reason applied to the Crick and Watson proposal -
Prior to 1953 William Astbury, Linus Pauling, Robert Corey and Rosalind Franklin were all suggesting models that were attached by means of the hydrogen bond. Glycosidic/covalent bonds become triumphant only with acceptance of Crick & Watson's un-natural architecture. To my mind their model would struggle to sustain itself without some pretty hefty bonds. Indeed every molecule is held in position by clamps and unnatural forces rather than falling into position via an effective geo-chemical architecture. Enzymes are surely biological automatons that read what is effectively a complex 3 dimensional molecular Braille; they are triggered to respond to and carry out their business via attraction and shape. Were there no recognisable regularity of shape they and their interlocutors would not only need brains with decision making abilities but also bolt cutters to carry out such actions as they automatedly require.
Epi-genetics would tie in with a structure being held together by hydrogen bonds. Not only would it increase energy efficient malleability but it would also facilitate the specific locational and structural changes needed to make those required transformations.