Mark E Curtis
The geometry of DNA: a structural revision
- critical reason applied to the Crick and Watson proposal -
Prior to 1953 William Astbury, Linus Pauling, Robert Corey and Rosalind Franklin were all suggesting models that were attached by means of the hydrogen bond. Glycosidic/covalent bonds become triumphant only with acceptance of Crick & Watson's un-natural architecture. Unsurprisingly their proposal would inevitably struggle to sustain itself without some pretty hefty bonds. Indeed every molecule in their model is held in position by clamps and unnatural forces instead of falling into position by means of a naturally effective and attractive geo-chemical architecture. Surely Enzymes must respond and carry out their business through attraction, shape and touch. Were there no accurate and detailed regularity of shape, and if all was indeed held together by covalent bonds, enzymes would need individual brains, not only with decision making abilities but also chainsaws and bolt cutters in order to make the slightest modification in carrying out their operations.
The concept of Epigenetics would also tie in with the idea of the entire structure being held together by hydrogen bonds… it would increase energy efficient malleability, and also facilitate the specific location and structural changes needed to make that transformation.